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Dokumenttyp:
journal article 
Autor(en):
van Helden, MJ; van Kooten, PJ; Bekker, CP; Gröne, A; Topham, DJ; Easton, AJ; Boog, CJ; Busch, DH; Zaiss, DM; Sijts, AJ 
Titel:
Pre-existing virus-specific CD8(+) T-cells provide protection against pneumovirus-induced disease in mice. 
Abstract:
Pneumoviruses such as pneumonia virus of mice (PVM), bovine respiratory syncytial virus (bRSV) or human (h)RSV are closely related pneumoviruses that cause severe respiratory disease in their respective hosts. It is well-known that T-cell responses are essential in pneumovirus clearance, but pneumovirus-specific T-cell responses also are important mediators of severe immunopathology. In this study we determined whether memory- or pre-existing, transferred virus-specific CD8(+) T-cells provide pr...    »
 
Zeitschriftentitel:
Vaccine 
Jahr:
2012 
Band / Volume:
30 
Heft / Issue:
45 
Seitenangaben Beitrag:
6382-8 
Sprache:
eng 
Print-ISSN:
0264-410X 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene