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Document type:
journal article 
Author(s):
Chatenoud, L; Warncke, K; Ziegler, AG 
Title:
Clinical immunologic interventions for the treatment of type 1 diabetes. 
Abstract:
Type 1 diabetes is an autoimmune disease, hence the rationale for immunotherapy to halt disease progression. Based on knowledge gained from other autoimmune diseases and from transplantation, the first immunointervention trials used immunosuppressive drugs, e.g., cyclosporin, in patients with recently diagnosed type 1 diabetes. Although remarkable, the effect vanished following drug withdrawal. Efforts were then devoted to devise strategies to induce/restore self-tolerance and avoid chronic immu...    »
 
Journal title abbreviation:
Cold Spring Harb Perspect Med 
Year:
2012 
Journal volume:
Journal issue:
Language:
eng 
TUM Institution:
Kinderklinik und Poliklinik