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Dokumenttyp:
journal article 
Autor(en):
Baumhoer, D; Smida, J; Zillmer, S; Rosemann, M; Atkinson, MJ; Nelson, PJ; Jundt, G; Luettichau, IV; Nathrath, M 
Titel:
Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma. 
Abstract:
Hematogenous spread determines the outcome of osteosarcoma (OS) patients, but the pathogenesis of developing metastatic disease is still unclear. Chemokines are critical regulators of cell trafficking and adhesion, and have been reported to be aberrantly expressed and to correlate with an unfavorable prognosis and metastatic spread in several malignant tumors. The chemokine receptors CXCR4 and CXCR7 together with their common ligand CXCL12 form one of the most important chemokine axes in this co...    »
 
Zeitschriftentitel:
Mod Pathol 
Jahr:
2012 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
522-8 
Sprache:
eng 
Print-ISSN:
0893-3952 
TUM Einrichtung:
Kinderklinik und Poliklinik