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- Document type:
- Journal Article
- Author(s):
- Ipach, I; Mittag, F; Kopp, HG; Kunze, B; Wolf, P; Kluba, T
- Title:
- Clear-cell sarcoma of the soft tissue - a rare diagnosis with a fatal outcome.
- Abstract:
- IPACH I., MITTAG F., KOPP H.-G., KUNZE B., WOLF P. & KLUBA T. (2012) European Journal of Cancer Care21, 412-420 Clear-cell sarcoma of the soft tissue - a rare diagnosis with a fatal outcome Clear-cell sarcomas account for less than 1% of all soft tissue tumours. They most often occur in middle-aged adults as a deeply located lesion with predilection to the tendons and aponeuroses. The aim of the present study was to show possible influencing factors on the outcome after surgical treatment in a detailed case series. We reviewed the medical records of 11 patients with the diagnosis of a clear-cell sarcoma of the soft tissue. These cases were analysed with regard to age, gender, localisation, tumour size, recurrence free survival and overall survival. A minimum follow up of 12 months was achieved. The mean age at the point of diagnosis was 47.9 years. Metastases occurred after a mean of 19.2 months. In the cases with a tumour diameter >5 cm, metastases occurred earlier. When treated in a specialist centre, metastases occurred later. Patients died a mean of 18.4 months after developing metastatic disease. Patients with tumour size >5 cm at the point of primary diagnosis died earlier than patients with a tumour size <5 cm. It is important to detect clear-cell sarcomas as soon as possible and the final surgical treatment should be performed in a centre familiar with the treatment of soft tissue tumours not only to prolong overall survival, but also to treat the patient in a multiprofessional team.
- Journal title abbreviation:
- Eur J Cancer Care (Engl)
- Year:
- 2012
- Journal volume:
- 21
- Journal issue:
- 3
- Pages contribution:
- 412-20
- Language:
- eng
- Fulltext / DOI:
- doi:10.1111/j.1365-2354.2011.01318.x
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/22150806
- Print-ISSN:
- 0961-5423
- TUM Institution:
- Institut für Medizinische Statistik und Epidemiologie
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