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Dokumenttyp:
journal article 
Autor(en):
Ringelhan, M; Schmid, RM; Geisler, F 
Titel:
The NF-?B subunit RelA/p65 is dispensable for successful liver regeneration after partial hepatectomy in mice. 
Abstract:
The transcription factor NF-?B consisting of the subunits RelA/p65 and p50 is known to be quickly activated after partial hepatectomy (PH), the functional relevance of which is still a matter of debate. Current concepts suggest that activation of NF-?B is especially critical in non-parenchymal cells to produce cytokines (TNF, IL-6) to adequately prime hepatocytes to proliferate after PH, while NF-?B within hepatocytes mainly bears cytoprotective functions.To study the role of the NF-?B pathway i...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2012 
Band / Volume:
Heft / Issue:
10 
Seitenangaben Beitrag:
e46469 
Sprache:
eng 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik