Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Ramus, SJ; Antoniou, AC; Kuchenbaecker, KB; Soucy, P; Beesley, J; Chen, X; McGuffog, L; Sinilnikova, OM; Healey, S; Barrowdale, D; Lee, A; Thomassen, M; Gerdes, AM; Kruse, TA; Jensen, UB; Skytte, AB; Caligo, MA; Liljegren, A; Lindblom, A; Olsson, H; Kristoffersson, U; Stenmark-Askmalm, M; Melin, B; SWE-BRCA; Domchek, SM; Nathanson, KL; Rebbeck, TR; Jakubowska, A; Lubinski, J; Jaworska, K; Durda, K; Z?owocka, E; Gronwald, J; Huzarski, T; Byrski, T; Cybulski, C; Toloczko-Grabarek, A; Osorio, A; Be...    »
 
Titel:
Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. 
Abstract:
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four of these loci as potential modifiers of ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Four single-nucleotide polymorphisms (SNPs), rs10088218 (at 8q24), rs2665390 (at 3q25), rs717852 (at 2q31), and rs9303542 (at 17q21), were ge...    »
 
Zeitschriftentitel:
Hum Mutat 
Jahr:
2012 
Band / Volume:
33 
Heft / Issue:
Seitenangaben Beitrag:
690-702 
Sprache:
eng 
Print-ISSN:
1059-7794 
TUM Einrichtung:
Frauenklinik und Poliklinik