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Document type:
journal article 
Author(s):
Kleikers, PW; Wingler, K; Hermans, JJ; Diebold, I; Altenhöfer, S; Radermacher, KA; Janssen, B; Görlach, A; Schmidt, HH 
Title:
NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury. 
Abstract:
Ischemia/reperfusion injury (IRI) is crucial in the pathology of major cardiovascular diseases, such as stroke and myocardial infarction. Paradoxically, both the lack of oxygen during ischemia and the replenishment of oxygen during reperfusion can cause tissue injury. Clinical outcome is also determined by a third, post-reperfusion phase characterized by tissue remodeling and adaptation. Increased levels of reactive oxygen species (ROS) have been suggested to be key players in all three phases....    »
 
Journal title abbreviation:
J Mol Med 
Year:
2012 
Journal volume:
90 
Journal issue:
12 
Pages contribution:
1391-406 
Language:
eng 
Print-ISSN:
0946-2716 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler