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Dokumenttyp:
journal article 
Autor(en):
Wang-Sattler, R; Yu, Z; Herder, C; Messias, AC; Floegel, A; He, Y; Heim, K; Campillos, M; Holzapfel, C; Thorand, B; Grallert, H; Xu, T; Bader, E; Huth, C; Mittelstrass, K; Döring, A; Meisinger, C; Gieger, C; Prehn, C; Roemisch-Margl, W; Carstensen, M; Xie, L; Yamanaka-Okumura, H; Xing, G; Ceglarek, U; Thiery, J; Giani, G; Lickert, H; Lin, X; Li, Y; Boeing, H; Joost, HG; de Angelis, MH; Rathmann, W; Suhre, K; Prokisch, H; Peters, A; Meitinger, T; Roden, M; Wichmann, HE; Pischon, T; Adamski, J; Il...    »
 
Titel:
Novel biomarkers for pre-diabetes identified by metabolomics. 
Abstract:
Type 2 diabetes (T2D) can be prevented in pre-diabetic individuals with impaired glucose tolerance (IGT). Here, we have used a metabolomics approach to identify candidate biomarkers of pre-diabetes. We quantified 140 metabolites for 4297 fasting serum samples in the population-based Cooperative Health Research in the Region of Augsburg (KORA) cohort. Our study revealed significant metabolic variation in pre-diabetic individuals that are distinct from known diabetes risk indicators, such as glyco...    »
 
Zeitschriftentitel:
Mol Syst Biol 
Jahr:
2012 
Band / Volume:
Seitenangaben Beitrag:
615 
Sprache:
eng 
TUM Einrichtung:
hrungsmedizin