Pfab, F; Valet, M; Napadow, V; Tölle, TR; Behrendt, H; Ring, J; Darsow, U
Itch and the brain.
The sensation of itch - defined as unpleasant sensation inducing the urge to scratch - is processed by a network of different brain regions contributing to the encoding of sensory, emotional, attention-dependent, cognitive-evaluative and motivational patterns. Patients with atopic eczema show different activation patterns and kinetics compared to healthy volunteers. This review summarizes current studies investigating itch in the brain.