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Dokumenttyp:
journal article 
Autor(en):
Mascetta, G; di Mola, FF; Tavano, F; Selvaggi, F; Giese, N; Bassi, C; Büchler, MW; Friess, H; di Sebastiano, P 
Titel:
Substance P and neprilysin in chronic pancreatitis. 
Abstract:
We aimed to analyze substance P (SP) and neprilysin (NEP), the membrane metallopeptidase that degrades SP, in chronic pancreatitis (CP).SP and NEP mRNA levels were analyzed by qRT-PCR in tissue samples from 30 patients with CP and 8 organ donors. In addition, SP serum levels were determined before and after surgery in the same patients, by means of a competitive ELISA assay. Genetic and epigenetic analyses of the NEP gene were also performed.SP mRNA expression levels were higher in CP tissues co...    »
 
Zeitschriftentitel:
Eur Surg Res 
Jahr:
2012 
Band / Volume:
48 
Heft / Issue:
Seitenangaben Beitrag:
131-8 
Sprache:
eng 
Print-ISSN:
0014-312X 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik