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Dokumenttyp:
journal article 
Autor(en):
Skorokhod, A; Bachmann, J; Giese, NA; Martignoni, ME; Krakowski-Roosen, H 
Titel:
Real-imaging cDNA-AFLP transcript profiling of pancreatic cancer patients: Egr-1 as a potential key regulator of muscle cachexia. 
Abstract:
Cancer cachexia is a progressive wasting syndrome and the most prevalent characteristic of cancer in patients with advanced pancreatic adenocarcinoma. We hypothesize that genes expressed in wasted skeletal muscle of pancreatic cancer patients may determine the initiation and severity of cachexia syndrome.We studied gene expression in skeletal muscle biopsies from pancreatic cancer patients with and without cachexia utilizing Real-Imaging cDNA-AFLP-based transcript profiling for genome-wide expre...    »
 
Zeitschriftentitel:
BMC Cancer 
Jahr:
2012 
Band / Volume:
12 
Seitenangaben Beitrag:
265 
Sprache:
eng 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik