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Dokumenttyp:
journal article 
Autor(en):
Schauer, MC; Stoecklein, NH; Theisen, J; Kröpil, F; Baldus, S; Hoelscher, A; Feith, M; Bölke, E; Matuschek, C; Budach, W; Knoefel, WT 
Titel:
The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging. 
Abstract:
In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induces functional changes with decreased mesenchymal and increased epithelial markers. In order to study this tumor suppressor activity of Eph B3 in esophageal adenocarcinoma we analyzed the simu...    »
 
Zeitschriftentitel:
Eur J Med Res 
Jahr:
2012 
Band / Volume:
17 
Seitenangaben Beitrag:
10 
Sprache:
eng 
Print-ISSN:
0949-2321 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik