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Dokumenttyp:
journal article 
Autor(en):
Erkan, M; Hausmann, S; Michalski, CW; Schlitter, AM; Fingerle, AA; Dobritz, M; Friess, H; Kleeff, J 
Titel:
How fibrosis influences imaging and surgical decisions in pancreatic cancer. 
Abstract:
Our understanding of pancreatic ductal adenocarcinoma (PDAC) is shifting away from a disease of malignant ductal cells-only, toward a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment. This change has led to intensification of research focusing on the fibrotic stroma of PDAC. Pancreatic stellate cells (PSCs) are the main fibroblastic cells of the pancreas which are responsible for producing the desmoplasia in chronic pancreatitis (CP) and...    »
 
Zeitschriftentitel:
Front Physiol 
Jahr:
2012 
Band / Volume:
Seitenangaben Beitrag:
389 
Sprache:
eng 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie; r Radiologie