Enantio- and Regioselective Epoxidation of Olefinic Double Bonds in Quinolones, Pyridones, and Amides Catalyzed by a Ruthenium Porphyrin Catalyst with a Hydrogen Bonding Site

Fackler, P.; Huber, S. M.; Bach, T.

doi:10.1021/ja305890c

Benutzer: Gast

Dokumenttyp:: Journal Article
Autor(en):: Fackler, P.; Huber, S. M.; Bach, T.
Titel:: Enantio- and Regioselective Epoxidation of Olefinic Double Bonds in Quinolones, Pyridones, and Amides Catalyzed by a Ruthenium Porphyrin Catalyst with a Hydrogen Bonding Site
Abstract:: An array of differently substituted 3-alkenylquinolones was synthesized, and the enantio- and regioselectivity of their Ru-catalyzed epoxidation were studied. A precursor ruthenium(II) complex with a chiral tricyclic gamma-lactam skeleton (octahydro-1H-4,7-methanoisoindol-1-one) was available by Sonogashira cross-coupling with a monobromo-substituted ruthenium(II) porphyrin. Enantioselective epoxidation reactions (60-83
Kongresstitel:: ISI Document Delivery No.: 981CH Times Cited: 5 Cited Reference Count: 108 Fackler, Philipp Huber, Stefan M. Bach, Thorsten Huber, Stefan/F-7660-2011 Deutsche Forschungsgemeinschaft [Ba 1372-17]; TUM Graduate School; Fonds der Chemischen Industrie This project was supported by the Deutsche Forschungsgemeinschaft (Ba 1372-17) and by the TUM Graduate School. We thank Wacker-Chemie (Munich) for the donation of chemicals. S.M.H. thanks the Fonds der Chemischen Industrie for a Liebig fellowship. 5 Amer chemical soc Washington «
ISI Document Delivery No.: 981CH Times Cited: 5 Cited Reference Count: 108 Fackler, Philipp Huber, Stefan M. Bach, Thorsten Huber, Stefan/F-7660-2011 Deutsche Forschungsgemeinschaft [Ba 1372-17]; TUM Graduate School; Fonds der Chemischen Industrie This project was supported by the Deutsche Forschungsgemeinschaft (Ba 1372-17) and by the TUM Graduate School. We thank Wacker-Chemie (Munich) for the donation of chemicals. S.M.H. thanks the Fonds der Chemischen Industrie for a Liebig fellowship. 5... »
Zeitschriftentitel:: Journal of the American Chemical Society
Jahr:: 2012
Band / Volume:: 134
Heft / Issue:: 30
Seitenangaben Beitrag:: 12869-12878
Volltext / DOI:: doi:10.1021/ja305890c
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