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Dokumenttyp:
journal article 
Autor(en):
Tresilwised, N; Pithayanukul, P; Holm, PS; Schillinger, U; Plank, C; Mykhaylyk, O 
Titel:
Effects of nanoparticle coatings on the activity of oncolytic adenovirus-magnetic nanoparticle complexes. 
Abstract:
Limitations to adenovirus infectivity can be overcome by association with magnetic nanoparticles and enforced infection by magnetic field influence. Here we examined three core-shell-type iron oxide magnetic nanoparticles differing in their surface coatings, particle sizes and magnetic properties for their ability to enhance the oncolytic potency of adenovirus Ad520 and to stabilize it against the inhibitory effects of serum or a neutralizing antibody. It was found that the physicochemical prope...    »
 
Zeitschriftentitel:
Biomaterials 
Jahr:
2012 
Band / Volume:
33 
Heft / Issue:
Seitenangaben Beitrag:
256-69 
Sprache:
eng 
Print-ISSN:
0142-9612 
TUM Einrichtung:
r experimentelle Onkologie und Therapieforschung