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Dokumenttyp:
journal article 
Autor(en):
Alexopoulos, P; Richter-Schmidinger, T; Horn, M; Maus, S; Reichel, M; Sidiropoulos, C; Rhein, C; Lewczuk, P; Doerfler, A; Kornhuber, J 
Titel:
Hippocampal volume differences between healthy young apolipoprotein E ?2 and ?4 carriers. 
Abstract:
The apolipoprotein E (APOE) ?4 allele is the major genetic risk factor for the development of late-onset Alzheimer's disease (AD), whereas the presence of the APOE ?2 allele seems to confer protection. Here, we report that healthy young APOE ?4 carriers have statistically significantly smaller hippocampal volumes than APOE ?2 carriers, while no differences were detected between the two groups in memory performance. The difference in hippocampal morphology is cognitively/clinically silent in youn...    »
 
Zeitschriftentitel:
J Alzheimers Dis 
Jahr:
2011 
Band / Volume:
26 
Heft / Issue:
Seitenangaben Beitrag:
207-10 
Sprache:
eng 
Print-ISSN:
1387-2877 
TUM Einrichtung:
r Psychiatrie und Psychotherapie