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Dokumenttyp:
journal article 
Autor(en):
Berg, D; Malinowsky, K; Reischauer, B; Wolff, C; Becker, KF 
Titel:
Use of formalin-fixed and paraffin-embedded tissues for diagnosis and therapy in routine clinical settings. 
Abstract:
Formalin-fixed and paraffin-embedded (FFPE) tissues are used routinely everyday in hospitals world-wide for histopathological diagnosis of diseases like cancer. Due to formalin-induced cross-linking of proteins, FFPE tissues present a particular challenge for proteomic analysis. Nevertheless, there has been recent progress for extraction-based protein analysis in these tissues. Novel tools developed in the last few years are urgently needed because precise protein biomarker quantification in cli...    »
 
Zeitschriftentitel:
Methods Mol Biol 
Jahr:
2011 
Band / Volume:
785 
Seitenangaben Beitrag:
109-22 
Sprache:
eng 
Print-ISSN:
1064-3745 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie