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Dokumenttyp:
journal article 
Autor(en):
Hermann, G; Konukiewitz, B; Schmitt, A; Perren, A; Klöppel, G 
Titel:
Hormonally defined pancreatic and duodenal neuroendocrine tumors differ in their transcription factor signatures: expression of ISL1, PDX1, NGN3, and CDX2. 
Abstract:
We recently identified the transcription factor (TF) islet 1 gene product (ISL1) as a marker for well-differentiated pancreatic neuroendocrine tumors (P-NETs). In order to better understand the expression of the four TFs, ISL1, pancreatico-duodenal homeobox 1 gene product (PDX1), neurogenin 3 gene product (NGN3), and CDX-2 homeobox gene product (CDX2), that mainly govern the development and differentiation of the pancreas and duodenum, we studied their expression in hormonally defined P-NETs and...    »
 
Zeitschriftentitel:
Virchows Arch 
Jahr:
2011 
Band / Volume:
459 
Heft / Issue:
Seitenangaben Beitrag:
147-54 
Sprache:
eng 
Print-ISSN:
0945-6317 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie