Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
International Multiple Sclerosis Genetics Consortium; Leppa, V; Surakka, I; Tienari, PJ; Elovaara, I; Compston, A; Sawcer, S; Robertson, N; De Jager, PL; Aubin, C; Hafler, DA; Oturai, AB; Bach Søndergaard, H; Sellebjerg, F; Soelberg Sørensen, P; Hemmer, B; Cepok, S; Winkelmann, J; Wichmann, HE; Comabella, M; Bustamante, MF; Montalban, X; Olsson, T; Kockum, I; Hillert, J; Alfredsson, L; Goris, A; Dubois, B; Mero, IL; Smestad, C; Celius, EG; Harbo, HF; D'Alfonso, S; Bergamaschi, L; Leone, M; Risto...    »
 
Titel:
The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study. 
Abstract:
In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). To refine our understanding of these associations we sought to replicate these findings in a large more extensive independent sample set of 11 populations of European origin.We calculated individual and combined associations using a meta-analysis m...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2011 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e18813 
Sprache:
eng 
TUM Einrichtung:
Neurologische Klinik und Poliklinik