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Dokumenttyp:
journal article 
Autor(en):
Lalive, PH; Neuhaus, O; Benkhoucha, M; Burger, D; Hohlfeld, R; Zamvil, SS; Weber, MS 
Titel:
Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action. 
Abstract:
Glatiramer acetate is a synthetic, random copolymer widely used as a first-line agent for the treatment of relapsing-remitting multiple sclerosis (MS). While earlier studies primarily attributed its clinical effect to a shift in the cytokine secretion of CD4+ T helper (T(h)) cells, growing evidence in MS and its animal model, experimental autoimmune encephalomyelitis (EAE), suggests that glatiramer acetate treatment is associated with a broader immunomodulatory effect on cells of both the innate...    »
 
Zeitschriftentitel:
CNS Drugs 
Jahr:
2011 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
401-14 
Sprache:
eng 
Print-ISSN:
1172-7047 
TUM Einrichtung:
Neurologische Klinik und Poliklinik