User: Guest  Login
Document type:
journal article 
Author(s):
Ari, F; Napieralski, R; Ulukaya, E; Dere, E; Colling, C; Honert, K; Krüger, A; Kiechle, M; Schmitt, M 
Title:
Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine. 
Abstract:
Epigenetic drugs are promising add-ons to cancer treatment; still, adverse effects concerning tumour promotion have been reported occasionally. In this in vitro study, we investigated the effect of combination treatment of decitabine with anthracycline-based chemotherapy [5-fluorouracil plus epirubicine plus cyclophosphamide (FEC)] on viability and metastatic activity of breast cancer cell lines, MDA-MB-231 (estrogen receptor-negative) and MCF-7 (estrogen receptor-positive). The effect of decit...    »
 
Journal title abbreviation:
Cell Biochem Funct 
Year:
2011 
Journal volume:
29 
Journal issue:
Pages contribution:
651-9 
Language:
eng 
Print-ISSN:
0263-6484 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung