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Document type:
journal article 
Author(s):
Fuchs, H; Gailus-Durner, V; Adler, T; Aguilar-Pimentel, JA; Becker, L; Calzada-Wack, J; Da Silva-Buttkus, P; Neff, F; Götz, A; Hans, W; Hölter, SM; Horsch, M; Kastenmüller, G; Kemter, E; Lengger, C; Maier, H; Matloka, M; Möller, G; Naton, B; Prehn, C; Puk, O; Rácz, I; Rathkolb, B; Römisch-Margl, W; Rozman, J; Wang-Sattler, R; Schrewe, A; Stöger, C; Tost, M; Adamski, J; Aigner, B; Beckers, J; Behrendt, H; Busch, DH; Esposito, I; Graw, J; Illig, T; Ivandic, B; Klingenspor, M; Klopstock, T; Kremmer...    »
 
Title:
Mouse phenotyping. 
Abstract:
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which mimic human conditions. Due to pleiotropic effects, one gene may have different functions in different organ systems or time points during developme...    »
 
Journal title abbreviation:
Methods 
Year:
2011 
Journal volume:
53 
Journal issue:
Pages contribution:
120-35 
Language:
eng 
Print-ISSN:
1046-2023 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene ; Institut für Molekulare Allergologie und Umweltforschung ; Institut für Allgemeine Pathologie und pathologische Anatomie ; Klinik und Poliklinik für Dermatologie und Allergologie