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Dokumenttyp:
journal article 
Autor(en):
Weber, MS; Hemmer, B; Cepok, S 
Titel:
The role of antibodies in multiple sclerosis 
Abstract:
B cells, plasma cells, and antibodies are commonly found in active central nervous system (CNS) lesions in patients with multiple sclerosis (MS). B cells isolated from CNS lesions as well as from the cerebrospinal fluid (CSF) show signs of clonal expansion and hypermutation, suggesting their local activation. Plasma blasts and plasma cells maturating from these B cells were recently identified to contribute to the development of oligoclonal antibodies produced within the CSF, which remain a diag...    »
 
Zeitschriftentitel:
BBA - MOL BASIS DIS 
Jahr:
2011 
Band / Volume:
1812 
Heft / Issue:
Seitenangaben Beitrag:
239-245 
Sprache:
eng 
Print-ISSN:
0925-4439 
TUM Einrichtung:
Neurologische Klinik und Poliklinik