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Dokumenttyp:
journal article 
Autor(en):
Pellkofer, HL; Krumbholz, M; Berthele, A; Hemmer, B; Gerdes, LA; Havla, J; Bittner, R; Canis, M; Meinl, E; Hohlfeld, R; Kuempfel, T 
Titel:
Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab. 
Abstract:
Neuromyelitis optica (NMO) is a severe autoimmune disease targeting optic nerves and spinal cord. The monoclonal anti-CD20 B-cell antibody rituximab is an emerging therapeutic option in NMO. However, neither long-term efficacy or safety of rituximab, nor the correlation between B-cell counts, B-cell fostering cytokines, aquaporin-4 antibodies (AQP4-ab), and disease activity in NMO, have been investigated prospectively.We performed a prospective long-term cohort study of 10 patients with NMO who...    »
 
Zeitschriftentitel:
Neurology 
Jahr:
2011 
Band / Volume:
76 
Heft / Issue:
15 
Seitenangaben Beitrag:
1310-5 
Sprache:
eng 
Print-ISSN:
0028-3878 
TUM Einrichtung:
Neurologische Klinik und Poliklinik