Comparison of sequential and helical scanning for radiation dose and image quality: results of the Prospective Multicenter Study on Radiation Dose Estimates of Cardiac CT Angiography (PROTECTION) I Study.

Bischoff, B; Hein, F; Meyer, T; Krebs, M; Hadamitzky, M; Martinoff, S; Schömig, A; Hausleiter, J

doi:10.2214/AJR.09.3543

journal article

Dokumenttyp:: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Article
Autor(en):: Bischoff, B; Hein, F; Meyer, T; Krebs, M; Hadamitzky, M; Martinoff, S; Schömig, A; Hausleiter, J
Titel:: Comparison of sequential and helical scanning for radiation dose and image quality: results of the Prospective Multicenter Study on Radiation Dose Estimates of Cardiac CT Angiography (PROTECTION) I Study.
Abstract:: Concerns have been raised about the radiation exposure of coronary CT angiography (CTA). Recently, a prospective ECG-triggered sequential coronary CTA technique was developed to reduce exposure to ionizing radiation. The purpose of this analysis was to determine the impact of a sequential scanning technique on image quality and radiation dose in a prespecified subgroup analysis of the Prospective Multicenter Study on Radiation Dose Estimates of Cardiac CT Angiography I (PROTECTION I) Study when compared with a standard helical scanning technique.This analysis comprises 685 64-MDCT coronary angiography studies of 47 international study sites in which the image quality was assessed by an experienced coronary CTA investigator using a 4-point score (1 = nondiagnostic, 4 = excellent image quality). Image quality was analyzed in all patients studied with the sequential scanning mode (n = 99) and in randomly selected patients of the population studied with the helical acquisition mode (n = 586). Radiation dose estimates were derived from the dose-length product (DLP) and a conversion coefficient for the chest (0.014 mSv x mGy(-1) x cm(-1)).Although the sequential scanning mode significantly reduced radiation dose estimates by 68% from 11.2 mSv for the helical mode to 3.6 mSv for the sequential mode (p < 0.001), the median diagnostic image quality scores were comparable in both groups. The median diagnostic score for both scanning modes was 3.5 (interquartile range: sequential vs helical mode, 3.25-3.75 vs 3.0-3.75, respectively; p = 0.62).The results of the PROTECTION I Study suggest that the prospective ECG-triggered sequential coronary CTA technique significantly reduces radiation dose without impairing image quality when compared with the standard retrospective helical data acquisition in patients with a low and stable heart rate.
Zeitschriftentitel:: AJR Am J Roentgenol
Jahr:: 2010
Band / Volume:: 194
Heft / Issue:: 6
Seitenangaben Beitrag:: 1495-9
Sprache:: eng
Volltext / DOI:: doi:10.2214/AJR.09.3543
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/20489088
Print-ISSN:: 0361-803X
TUM Einrichtung:: I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Radiologie
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