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Document type:
journal article 
Author(s):
Arzberger, S; Hösel, M; Protzer, U 
Title:
Apoptosis of hepatitis B virus-infected hepatocytes prevents release of infectious virus. 
Abstract:
Apoptosis of infected cells is critically involved in antiviral defense. Apoptosis, however, may also support the release and spread of viruses. Although the elimination of infected hepatocytes is required to combat hepatitis B virus (HBV) infection, it is still unknown which consequences hepatocyte apoptosis has for the virus and whether or not it is advantageous to the virus. To study this, we designed a cell culture model consisting of both HBV-producing cell lines and primary human hepatocyt...    »
 
Journal title abbreviation:
J Virol 
Year:
2010 
Journal volume:
84 
Journal issue:
22 
Pages contribution:
11994-2001 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Institut für Virologie