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Dokumenttyp:
journal article 
Autor(en):
Kimura, T; Ishikawa, K; Sakasegawa, Y; Teruya, K; Sata, T; Schätzl, H; Doh-ura, K 
Titel:
GABAA receptor subunit beta1 is involved in the formation of protease-resistant prion protein in prion-infected neuroblastoma cells. 
Abstract:
Gamma-aminobutyric acid type A (GABAA) receptor beta1 (gabrb1), a subunit of GABAA receptors involved in inhibitory effects on neurotransmission, was found to associate with the formation of protease-resistant prion protein in prion-infected neuroblastoma cells. Silencing of gabrb1 gene expression significantly decreased the abnormal prion protein level but paradoxically increased the normal prion protein level. Treatment with a gabrb1-specific inhibitor, salicylidene salicylhydrazide, dose-depe...    »
 
Zeitschriftentitel:
FEBS Lett 
Jahr:
2010 
Band / Volume:
584 
Heft / Issue:
Seitenangaben Beitrag:
1193-8 
Sprache:
eng 
Print-ISSN:
0014-5793 
TUM Einrichtung:
r Virologie