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Dokumenttyp:
journal article 
Autor(en):
Meyer, NH; Tripsianes, K; Vincendeau, M; Madl, T; Kateb, F; Brack-Werner, R; Sattler, M 
Titel:
Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain. 
Abstract:
Sam68 (Src-associated during mitosis, 68 kDa) is a prototypical member of the STAR (signal transducer and activator of RNA) family of RNA-binding proteins. STAR proteins bind mRNA targets and modulate cellular processes such as cell cycle regulation and tissue development in response to extracellular signals. Sam68 has been shown to modulate alternative splicing of the pre-mRNAs of CD44 and Bcl-xL, which are linked to tumor progression and apoptosis. Sam68 and other STAR proteins recognize bipar...    »
 
Zeitschriftentitel:
J Biol Chem 
Jahr:
2010 
Band / Volume:
285 
Heft / Issue:
37 
Seitenangaben Beitrag:
28893-901 
Sprache:
eng 
Print-ISSN:
0021-9258 
TUM Einrichtung:
r Virologie