User: Guest  Login
Document type:
journal article 
Author(s):
Schmid, TE; Dollinger, G; Beisker, W; Hable, V; Greubel, C; Auer, S; Mittag, A; Tarnok, A; Friedl, AA; Molls, M; Röper, B 
Title:
Differences in the kinetics of gamma-H2AX fluorescence decay after exposure to low and high LET radiation. 
Abstract:
In order to obtain more insight into heavy ion tumour therapy, some features of the underlying molecular mechanisms controlling the cellular response to high linear energy transfer (LET) radiation are currently analysed.We analysed the decay of the integrated fluorescence intensity of gamma-H2AX (phosphorylated histone H2AX) which is thought to reflect the repair kinetics of radiation-induced DNA double-strand breaks (DSB) using Laser-Scanning-Cytometry. Asynchronous human HeLa cells were irradi...    »
 
Journal title abbreviation:
Int J Radiat Biol 
Year:
2010 
Journal volume:
86 
Journal issue:
Pages contribution:
682-91 
Language:
eng 
Print-ISSN:
0955-3002 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie