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Document type:
journal article 
Author(s):
Swirski, FK; Wildgruber, M; Ueno, T; Figueiredo, JL; Panizzi, P; Iwamoto, Y; Zhang, E; Stone, JR; Rodriguez, E; Chen, JW; Pittet, MJ; Weissleder, R; Nahrendorf, M 
Title:
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. 
Abstract:
Rates of graft rejection are high among recipients of heart transplants. The onset and progression of clinically significant heart transplant rejection are currently monitored by serial biopsy, but this approach is highly invasive and lacks sensitivity. Here, we have developed what we believe to be a new technique to measure organ rejection noninvasively that involves the exploration of tissue-infiltrating leukocytes as biomarker sources for diagnostic imaging. Specifically, we profiled the myel...    »
 
Journal title abbreviation:
J Clin Invest 
Year:
2010 
Journal volume:
120 
Journal issue:
Pages contribution:
2627-34 
Language:
eng 
Print-ISSN:
0021-9738 
TUM Institution:
ntgendiagnostik