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Document type:
journal article 
Author(s):
Davis, JM; Giakas, WJ; Qu, J; Prasad, P; Leucht, S 
Title:
Should we treat depression with drugs or psychological interventions? A reply to Ioannidis. 
Abstract:
We reply to the Ioannidis's paper "Effectiveness of antidepressants; an evidence based myth constructed from a thousand controlled trials." We disagree that antidepressants have no greater efficacy than placebo. We present the efficacy from hundreds of trials in terms of the percentage of patients with a substantial clinical response (a 50% improvement or more symptomatic reduction). This meta-analysis finds that 42-70% of depressed patients improve with drug and 21%-39% improve with placebo. T...    »
 
Journal title abbreviation:
Philos Ethics Humanit Med 
Year:
2011 
Journal volume:
Pages contribution:
Language:
eng 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie