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Document type:
journal article 
Author(s):
Rauser, S; Marquardt, C; Balluff, B; Deininger, SO; Albers, C; Belau, E; Hartmer, R; Suckau, D; Specht, K; Ebert, MP; Schmitt, M; Aubele, M; Ho?fler, H; Walch, A 
Title:
Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry. 
Abstract:
Clinical laboratory testing for HER2 status in breast cancer tissues is critically important for therapeutic decision making. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a powerful tool for investigating proteins through the direct and morphology-driven analysis of tissue sections. We hypothesized that MALDI-IMS may determine HER2 status directly from breast cancer tissues. Breast cancer tissues (n = 48) predefined for HER2 status were subjected to MALD...    »
 
Journal title abbreviation:
J Proteome Res 
Year:
2010 
Journal volume:
Journal issue:
Pages contribution:
1854-63 
Language:
eng 
Print-ISSN:
1535-3893 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie ; II. Medizinische Klinik und Poliklinik