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Document type:
journal article 
Author(s):
Wiech, K; Lin, CS; Brodersen, KH; Bingel, U; Ploner, M; Tracey, I 
Title:
Anterior insula integrates information about salience into perceptual decisions about pain. 
Abstract:
The decision as to whether a sensation is perceived as painful does not only depend on sensory input but also on the significance of the stimulus. Here, we show that the degree to which an impending stimulus is interpreted as threatening biases perceptual decisions about pain and that this bias toward pain manifests before stimulus encounter. Using functional magnetic resonance imaging we investigated the neural mechanisms underlying the influence of an experimental manipulation of threat on the...    »
 
Journal title abbreviation:
J Neurosci 
Year:
2010 
Journal volume:
30 
Journal issue:
48 
Pages contribution:
16324-31 
Language:
eng 
Print-ISSN:
0270-6474 
TUM Institution:
Neurologische Klinik und Poliklinik