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Document type:
journal article 
Author(s):
Sellner, J; Weber, MS; Vollmar, P; Mattle, HP; Hemmer, B; Stüve, O 
Title:
The combination of interferon-beta and HMG-CoA reductase inhibition in multiple sclerosis: enthusiasm lost too soon? 
Abstract:
Recent studies support the notion that statins, widely prescribed cholesterol-lowering agents, may target key elements in the immunological cascade leading to inflammation and tissue damage in the pathogenesis of multiple sclerosis (MS). Compelling experimental and observational clinical studies highlighted the possibility that statins may also exert immunomodulatory synergy with approved MS drugs, resulting in several randomized clinical trials testing statins in combination with interferon-bet...    »
 
Journal title abbreviation:
CNS Neurosci Ther 
Year:
2010 
Journal volume:
16 
Journal issue:
Pages contribution:
362-73 
Language:
eng 
Print-ISSN:
1755-5930 
TUM Institution:
Neurologische Klinik und Poliklinik