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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Meggendorfer, M; Weierich, C; Wolff, H; Brack-Werner, R; Cremer, T 
Title:
Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters. 
Abstract:
A new experimental approach was designed to test different predictions of current models of the nuclear architecture with respect to the topography of transcription. We constructed a plasmid, termed pIndi, which carries a reporter gene coding for a red cytoplasmic fluorescent reporter protein. Transcription of the reporter gene is regulated by the inducible promoter of the human immunodeficiency virus (HIV) and is strongly dependent on the HIV-1 Tat protein. Expressing the red fluorescent report...    »
 
Journal title abbreviation:
Chromosome Res 
Year:
2010 
Journal volume:
18 
Journal issue:
Pages contribution:
401-17 
Language:
eng 
Print-ISSN:
0967-3849 
TUM Institution:
Institut für Virologie