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Dokumenttyp:
journal article 
Autor(en):
Korn, T; Mitsdoerffer, M; Kuchroo, VK 
Titel:
Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis. 
Abstract:
Experimental autoimmune encephalomyelitis (EAE) is an animal model for multiple sclerosis (MS) that has shaped our understanding of autoimmune tissue inflammation in the central nervous system (CNS). Major therapeutic approaches to MS have been first validated in EAE. Nevertheless, EAE in all its modifications is not able to recapitulate the full range of clinical and histopathogenic aspects of MS. Furthermore, autoimmune reactions in EAE-prone rodent strains and MS patients may differ in terms...    »
 
Zeitschriftentitel:
Results Probl Cell Differ 
Jahr:
2010 
Band / Volume:
51 
Seitenangaben Beitrag:
43-74 
Sprache:
eng 
Print-ISSN:
0080-1844 
TUM Einrichtung:
Neurologische Klinik und Poliklinik