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Dokumenttyp:
journal article 
Autor(en):
Weber, MS; Hemmer, B 
Titel:
Cooperation of B cells and T cells in the pathogenesis of multiple sclerosis. 
Abstract:
B cells and T cells are two major players in the pathogenesis of multiple sclerosis (MS) and cooperate at various check points. B cells, besides serving as a source for antibody-secreting plasma cells, are efficient antigen presenting cells for processing of intact myelin antigen and subsequent activation and pro-inflammatory differentiation of T cells. This notion is supported by the immediate clinical benefit of therapeutic B cell depletion in MS, presumably abrogating development of encephali...    »
 
Zeitschriftentitel:
Results Probl Cell Differ 
Jahr:
2010 
Band / Volume:
51 
Seitenangaben Beitrag:
115-26 
Sprache:
eng 
Print-ISSN:
0080-1844 
TUM Einrichtung:
Neurologische Klinik und Poliklinik