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Document type:
journal article 
Author(s):
Lindauer, U; Leithner, C; Kaasch, H; Rohrer, B; Foddis, M; Füchtemeier, M; Offenhauser, N; Steinbrink, J; Royl, G; Kohl-Bareis, M; Dirnagl, U 
Title:
Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation. 
Abstract:
Recently, a universal, simple, and fail-safe mechanism has been proposed by which cerebral blood flow (CBF) might be coupled to oxygen metabolism during neuronal activation without the need for any tissue-based mechanism. According to this concept, vasodilation occurs by local erythrocytic release of nitric oxide or ATP wherever and whenever hemoglobin is deoxygenated, directly matching oxygen demand and supply in every tissue. For neurovascular coupling in the brain, we present experimental evi...    »
 
Journal title abbreviation:
J Cereb Blood Flow Metab 
Year:
2010 
Journal volume:
30 
Journal issue:
Pages contribution:
757-68 
Language:
eng 
Print-ISSN:
0271-678X 
TUM Institution:
Neurochirurgische Klinik und Poliklinik