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Dokumenttyp:
journal article 
Autor(en):
Rusai, K; Sollinger, D; Baumann, M; Wagner, B; Strobl, M; Schmaderer, C; Roos, M; Kirschning, C; Heemann, U; Lutz, J 
Titel:
Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury. 
Abstract:
Toll-like receptors (TLRs) are an evolutionarily conserved family of cell membrane receptors that are part of the innate immunity system playing an important role as a first response to tissue injury. TLR2 and TLR4 are constitutively expressed on renal epithelium, and their expression is enhanced following renal ischemia/reperfusion (I/R) injury. Genetic deletion of either TLR2 or TLR4 protects from renal I/R injury. However, it is not known whether deletion of both combined protects the kidney...    »
 
Zeitschriftentitel:
Pediatr Nephrol 
Jahr:
2010 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
853-60 
Sprache:
eng 
Print-ISSN:
0931-041X 
TUM Einrichtung:
r Nephrologie