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Dokumenttyp:
journal article 
Autor(en):
Milosevic, S; Bachnick, B; Karim, K; Bornkamm, GW; Witter, K; Gerbitz, A; Mautner, J; Behrends, U 
Titel:
Identification of MHC II-restricted minor histocompatibility antigens after HLA-identical stem-cell transplantation. 
Abstract:
BACKGROUND: After allogeneic hematopoietic stem-cell transplantation (HSCT), donor-derived T cells may elicit graft-versus-host disease (GVHD) and graft-versus-tumor (GVT) responses. The main targets of GVHD and GVT responses after human leukocyte antigen (HLA)-identical HSCT are minor histocompatibility antigens (mHAgs), that is, polymorphic gene products in which recipient and donor differ. Thus, for increasing beneficial GVT and decreasing life-threatening GVHD responses, knowledge of the rel...    »
 
Zeitschriftentitel:
Transplantation 
Jahr:
2010 
Band / Volume:
90 
Heft / Issue:
Seitenangaben Beitrag:
1030-5 
Sprache:
eng 
Print-ISSN:
0041-1337 
TUM Einrichtung:
Kinderklinik und Poliklinik