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Document type:
journal article 
Author(s):
Otto, S; Hafner, S; Mast, G; Tischer, T; Volkmer, E; Schieker, M; Stürzenbaum, SR; von Tresckow, E; Kolk, A; Ehrenfeld, M; Pautke, C 
Title:
Bisphosphonate-related osteonecrosis of the jaw: is pH the missing part in the pathogenesis puzzle? 
Abstract:
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of bisphosphonate therapy, primarily diagnosed in patients with cancer and metastatic bone disease and receiving intravenous administrations of nitrogen-containing bisphosphonates. If diagnosis or treatment is delayed, BRONJ can develop to a severe and devastating disease. Numerous studies have focused on BRONJ, with possible pathomechanisms identified to be oversuppression of bone turnover, ischemia due to antiangiogenetic...    »
 
Journal title abbreviation:
J Oral Maxillofac Surg 
Year:
2010 
Journal volume:
68 
Journal issue:
Pages contribution:
1158-61 
Language:
eng 
Print-ISSN:
0278-2391 
TUM Institution:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie