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Dokumenttyp:
journal article 
Autor(en):
Koren-Michowitz, M; le Coutre, P; Duyster, J; Scheid, C; Panayiotidis, P; Prejzner, W; Rowe, JM; Schwarz, M; Goldschmidt, N; Nagler, A 
Titel:
Activity and tolerability of nilotinib: a retrospective multicenter analysis of chronic myeloid leukemia patients who are imatinib resistant or intolerant. 
Abstract:
Nilotinib is active in imatinib-resistant and -intolerant chronic myeloid leukemia patients and was recently approved for these indications.Data on the efficacy and safety of nilotinib treatment were collected from 2 phase 2 expanded access clinical trials with similar designs (CAMN107AIL01 and ENACT).Of 88 study patients (58 chronic, 11 accelerated, 19 blast crisis), the best responses to nilotinib were complete hematologic response (CHR) in 27%, partial cytogenetic response in 12%, complete cy...    »
 
Zeitschriftentitel:
Cancer 
Jahr:
2010 
Band / Volume:
116 
Heft / Issue:
19 
Seitenangaben Beitrag:
4564-72 
Sprache:
eng 
Print-ISSN:
0008-543X 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik