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Document type:
journal article 
Author(s):
Hoellein, A; Decker, T; Bogner, C; Oelsner, M; Hauswald, S; Peschel, C; Keller, U; Licht, T 
Title:
Expression of multidrug resistance-associated ABC transporters in B-CLL is independent of ZAP70 status. 
Abstract:
PURPOSE: To assess whether the poor prognosis of ZAP70-positive B-cell chronic lymphocytic leukemia (CLL) is associated with the overexpression of ABC transporter genes that are responsible for pleiotropic drug resistance. MATERIALS AND METHODS: The transcript level of ten drug transporters was analyzed using semiquantitative and quantitative RT-PCR in control hematopoietic cells, in 41 CLL patient samples and in 5 lymphoma cell lines. ZAP70 status was determined by immunoblotting. RESULTS: Of a...    »
 
Journal title abbreviation:
J Cancer Res Clin Oncol 
Year:
2010 
Journal volume:
136 
Journal issue:
Pages contribution:
403-10 
Language:
eng 
Print-ISSN:
0171-5216 
TUM Institution:
III. Medizinische Klinik und Poliklinik