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Dokumenttyp:
journal article 
Autor(en):
Bas, M; Hoffmann, TK; Tiemann, B; Dao, VT; Bantis, C; Balz, V; Schultz-Coulon, HJ; Stark, T; Schuler, P; Greve, J; Ivens, K; Bier, H; Kojda, G 
Titel:
Potential genetic risk factors in angiotensin-converting enzyme-inhibitor-induced angio-oedema. 
Abstract:
The pathophysiology of angiotensin-converting enzyme inhibitor (ACEi)-induced angio-oedema remains unclear. We have investigated the impact of ACE insertion/deletion (I/D) polymorphism in combination with serum ACE activity as well as the bradykinin B2 receptor 2/3 and c.C181T polymorphisms.We analysed the ACE I/D as well as bradykinin B2 (2/3 and C181T) receptor polymorphisms in 65 patients with documented episodes of ACEi-induced angio-oedema and 65 patients matched for age and sex being under...    »
 
Zeitschriftentitel:
Br J Clin Pharmacol 
Jahr:
2010 
Band / Volume:
69 
Heft / Issue:
Seitenangaben Beitrag:
179-86 
Sprache:
eng 
Print-ISSN:
0306-5251 
TUM Einrichtung:
Hals-, Nasen-, Ohrenklinik und Poliklinik