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Document type:
journal article 
Author(s):
Seismann, H; Blank, S; Braren, I; Greunke, K; Cifuentes, L; Grunwald, T; Bredehorst, R; Ollert, M; Spillner, E 
Title:
Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation. 
Abstract:
Hymenoptera venom allergy is known to cause life-threatening and sometimes fatal IgE-mediated anaphylactic reactions in allergic individuals. About 30-50% of patients with insect venom allergy have IgE antibodies that react with both honeybee and yellow jacket venom. Apart from true double sensitisation, IgE against cross-reactive carbohydrate determinants (CCD) are the most frequent cause of multiple reactivities severely hampering the diagnosis and design of therapeutic strategies by clinicall...    »
 
Journal title abbreviation:
Mol Immunol 
Year:
2010 
Journal volume:
47 
Journal issue:
Pages contribution:
799-808 
Language:
eng 
Print-ISSN:
0161-5890 
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie