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Dokumenttyp:
journal article 
Autor(en):
Stuart, PE; Nair, RP; Ellinghaus, E; Ding, J; Tejasvi, T; Gudjonsson, JE; Li, Y; Weidinger, S; Eberlein, B; Gieger, C; Wichmann, HE; Kunz, M; Ike, R; Krueger, GG; Bowcock, AM; Mrowietz, U; Lim, HW; Voorhees, JJ; Abecasis, GR; Weichenthal, M; Franke, A; Rahman, P; Gladman, DD; Elder, JT 
Titel:
Genome-wide association analysis identifies three psoriasis susceptibility loci. 
Abstract:
We carried out a meta-analysis of two recent psoriasis genome-wide association studies with a combined discovery sample of 1,831 affected individuals (cases) and 2,546 controls. One hundred and two loci selected based on P value rankings were followed up in a three-stage replication study including 4,064 cases and 4,685 controls from Michigan, Toronto, Newfoundland and Germany. In the combined meta-analysis, we identified three new susceptibility loci, including one at NOS2 (rs4795067, combined...    »
 
Zeitschriftentitel:
Nat Genet 
Jahr:
2010 
Band / Volume:
42 
Heft / Issue:
11 
Seitenangaben Beitrag:
1000-4 
Sprache:
eng 
Print-ISSN:
1061-4036 
TUM Einrichtung:
r Dermatologie und Allergologie