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Dokumenttyp:
journal article 
Autor(en):
Lubitz, S; Schober, W; Pusch, G; Effner, R; Klopp, N; Behrendt, H; Buters, JT 
Titel:
Polycyclic aromatic hydrocarbons from diesel emissions exert proallergic effects in birch pollen allergic individuals through enhanced mediator release from basophils. 
Abstract:
Diesel exhaust particles (DEPs) act as adjuvants in the immune system and contribute to the increased prevalence and morbidity of asthma and allergic rhinitis. Polycyclic aromatic hydrocarbons (PAHs) are major components of DEPs, which may be involved in the induction and enhancement of proallergic processes. In this study we explored adjuvant effects of DEP-PAHs on activation parameters of human basophils, fostering allergic inflammation through the release of preformed or granule-derived media...    »
 
Zeitschriftentitel:
Environ Toxicol 
Jahr:
2010 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
188-97 
Sprache:
eng 
Print-ISSN:
1520-4081 
TUM Einrichtung:
r Molekulare Allergologie und Umweltforschung; r Dermatologie und Allergologie