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Dokumenttyp:
journal article 
Autor(en):
Hong, X; Michalski, CW; Kong, B; Zhang, W; Raggi, MC; Sauliunaite, D; De Oliveira, T; Friess, H; Kleeff, J 
Titel:
ALCAM is associated with chemoresistance and tumor cell adhesion in pancreatic cancer. 
Abstract:
Cell-cell adhesion is a major factor in integrity of epithelia which is frequently disturbed in cancer leading to local invasion and distant metastasis.To define expression and function of activated leukocyte cell adhesion molecule (ALCAM, CD166) in pancreatic cancer and in pancreatic neuroendocrine tumors (PNET), microarray analyses, RT-PCR, immunohistochemistry, RNAi, adhesion, migration, invasion, and chemoresistance assays were used.We demonstrate that expression of ALCAM is altered and its...    »
 
Zeitschriftentitel:
J Surg Oncol 
Jahr:
2010 
Band / Volume:
101 
Heft / Issue:
Seitenangaben Beitrag:
564-9 
Sprache:
eng 
Print-ISSN:
0022-4790 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik