Login
- Document type:
- Journal Article; Research Support, Non-U.S. Gov't
- Author(s):
- Höfling, SB; Maschauer, S; Hübner, H; Gmeiner, P; Wester, HJ; Prante, O; Heinrich, MR
- Title:
- Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.
- Abstract:
- Radical (18)F-fluoroarylation with fluorine-18-labelled arenediazonium chlorides has been successfully applied to the radiochemical synthesis of the dopamine D(3)-selective ligand SH 317 ([(18)F]8). SH 317 has been evaluated as a new PET ligand candidate by in vivo experiments.
- Journal title abbreviation:
- Bioorg Med Chem Lett
- Year:
- 2010
- Journal volume:
- 20
- Journal issue:
- 23
- Pages contribution:
- 6933-7
- Language:
- eng
- Fulltext / DOI:
- doi:10.1016/j.bmcl.2010.09.142
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/21030255
- Print-ISSN:
- 0960-894X
- TUM Institution:
- Klinik und Poliklinik für Nuklearmedizin
BibTeX