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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Vallon, M; Rohde, F; Janssen, KP; Essler, M 
Title:
Tumor endothelial marker 5 expression in endothelial cells during capillary morphogenesis is induced by the small GTPase Rac and mediates contact inhibition of cell proliferation. 
Abstract:
Tumor endothelial marker (TEM) 5 is an adhesion G-protein-coupled receptor upregulated in endothelial cells during tumor and physiologic angiogenesis. So far, the mechanisms leading to upregulation of TEM5 and its function during angiogenesis have not been identified. Here, we report that TEM5 expression in endothelial cells is induced during capillary-like network formation on Matrigel, during capillary morphogenesis in a three-dimensional collagen I matrix, and upon confluence on a two-dimensi...    »
 
Journal title abbreviation:
Exp Cell Res 
Year:
2010 
Journal volume:
316 
Journal issue:
Pages contribution:
412-21 
Language:
eng 
Print-ISSN:
0014-4827 
TUM Institution:
Chirurgische Klinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin